Gene description for SPTBN4
Gene name spectrin, beta, non-erythrocytic 4
Gene symbol SPTBN4
Other names/aliases -
Species Bos taurus
 Database cross references - SPTBN4
ExoCarta ExoCarta_537578
Vesiclepedia VP_537578
Entrez Gene 537578
 SPTBN4 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SPTBN4
Molecular Function
    structural constituent of cytoskeleton GO:0005200 IEA
    phospholipid binding GO:0005543 IEA
    actin filament binding GO:0051015 IEA
Biological Process
    actin cytoskeleton organization GO:0030036 IEA
Subcellular Localization
    plasma membrane GO:0005886 IEA
    spectrin GO:0008091 IEA
    cell junction GO:0030054 IEA
    cortical actin cytoskeleton GO:0030864 IEA
    cell projection GO:0042995 IEA
 Experiment description of studies that identified SPTBN4 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SPTBN4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SPTBN4 is involved
No pathways found





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