Gene description for GRIN2B
Gene name glutamate receptor, ionotropic, N-methyl D-aspartate 2B
Gene symbol GRIN2B
Other names/aliases -
Species Bos taurus
 Database cross references - GRIN2B
ExoCarta ExoCarta_537804
Vesiclepedia VP_537804
Entrez Gene 537804
 GRIN2B identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for GRIN2B
Molecular Function
    NMDA glutamate receptor activity GO:0004972 IEA
    transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential GO:1904315 IEA
Biological Process
    monoatomic ion transport GO:0006811 IEA
    synaptic transmission, glutamatergic GO:0035249 IEA
    excitatory postsynaptic potential GO:0060079 IEA
    long-term synaptic potentiation GO:0060291 IEA
Subcellular Localization
    plasma membrane GO:0005886 IEA
    NMDA selective glutamate receptor complex GO:0017146 IEA
    postsynaptic membrane GO:0045211 IEA
    postsynaptic density membrane GO:0098839 IEA
 Experiment description of studies that identified GRIN2B in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GRIN2B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which GRIN2B is involved
No pathways found





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