Gene description for Tuba8
Gene name tubulin, alpha 8
Gene symbol Tuba8
Other names/aliases -
Species Mus musculus
 Database cross references - Tuba8
ExoCarta ExoCarta_53857
Entrez Gene 53857
UniProt Q9JJZ2  
 Tuba8 identified in exosomes derived from the following tissue/cell type
Oligodendrocytes 21136642    
 Gene ontology annotations for Tuba8
Molecular Function
    GTP binding GO:0005525 IEA
    GTPase activity GO:0003924 IEA
    nucleotide binding GO:0000166 IEA
    structural constituent of cytoskeleton GO:0005200 ISA
Biological Process
    protein polymerization GO:0051258 IEA
    microtubule cytoskeleton organization GO:0000226 ISA
    microtubule-based process GO:0007017 IEA
Subcellular Localization
    microtubule GO:0005874 ISA
    cytoplasm GO:0005737 IEA
    protein complex GO:0043234 IEA
    cytoskeleton GO:0005856 IEA
 Experiment description of studies that identified Tuba8 in exosomes
1
Experiment ID 33
ISEV standards
✔
EM|IEM
EV Biophysical techniques
✔
Alix|TSG101
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Oli-neu
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Tuba8
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tuba8 is involved
PathwayEvidenceSource
Translocation of GLUT4 to the plasma membrane IEA Reactome





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