Gene description for Cntn6
Gene name contactin 6
Gene symbol Cntn6
Other names/aliases NB-3
Species Mus musculus
 Database cross references - Cntn6
ExoCarta ExoCarta_53870
Vesiclepedia VP_53870
Entrez Gene 53870
UniProt Q9JMB8  
 Cntn6 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cntn6
Molecular Function
    protein binding GO:0005515 IPI
    cell-cell adhesion mediator activity GO:0098632 IBA
Biological Process
    cell adhesion GO:0007155 IEA
    homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 IBA
    Notch signaling pathway GO:0007219 IEA
    axon guidance GO:0007411 IBA
    positive regulation of Notch signaling pathway GO:0045747 IEP
    synapse organization GO:0050808 IBA
    dendrite self-avoidance GO:0070593 IBA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 TAS
    axon GO:0030424 IBA
    presynaptic membrane GO:0042734 IDA
    presynaptic membrane GO:0042734 IEP
    synapse GO:0045202 IBA
    side of membrane GO:0098552 IEA
    parallel fiber to Purkinje cell synapse GO:0098688 IDA
    parallel fiber to Purkinje cell synapse GO:0098688 IEP
    presynapse GO:0098793 IDA
    presynapse GO:0098793 IEP
 Experiment description of studies that identified Cntn6 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cntn6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cntn6 is involved
No pathways found





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