Gene description for USP8
Gene name ubiquitin specific peptidase 8
Gene symbol USP8
Other names/aliases -
Species Bos taurus
 Database cross references - USP8
ExoCarta ExoCarta_538743
Vesiclepedia VP_538743
Entrez Gene 538743
 USP8 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for USP8
Molecular Function
    cysteine-type deubiquitinase activity GO:0004843 IEA
Biological Process
    endosome organization GO:0007032 IEA
    Ras protein signal transduction GO:0007265 IEA
    protein K63-linked deubiquitination GO:0070536 IEA
    protein K48-linked deubiquitination GO:0071108 IEA
Subcellular Localization
    cytosol GO:0005829 IEA
    postsynaptic density GO:0014069 IEA
    extrinsic component of plasma membrane GO:0019897 IEA
    midbody GO:0030496 IEA
    extrinsic component of endosome membrane GO:0031313 IEA
    dendritic spine GO:0043197 IEA
 Experiment description of studies that identified USP8 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for USP8
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which USP8 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here