Gene description for PDE12
Gene name phosphodiesterase 12
Gene symbol PDE12
Other names/aliases 2'-PDE
Species Bos taurus
 Database cross references - PDE12
ExoCarta ExoCarta_538860
Entrez Gene 538860
UniProt Q08DF7  
 PDE12 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PDE12
Molecular Function
    poly(A)-specific ribonuclease activity GO:0004535 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    RNA phosphodiester bond hydrolysis, exonucleolytic GO:0090503 IEA
    mRNA processing GO:0006397 IEA
Subcellular Localization
    mitochondrial matrix GO:0005759 IEA
 Experiment description of studies that identified PDE12 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PDE12
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PDE12 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here