Gene description for ARPC4
Gene name actin related protein 2/3 complex, subunit 4, 20kDa
Gene symbol ARPC4
Other names/aliases -
Species Bos taurus
 Database cross references - ARPC4
ExoCarta ExoCarta_539459
Entrez Gene 539459
UniProt Q148J6  
 ARPC4 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ARPC4
Molecular Function
    structural constituent of cytoskeleton GO:0005200 IEA
    protein binding, bridging GO:0030674 IEA
    enzyme binding GO:0019899 IEA
    actin binding GO:0003779 IEA
Biological Process
    Arp2/3 complex-mediated actin nucleation GO:0034314 IEA
    actin filament polymerization GO:0030041 IEA
Subcellular Localization
    cytosol GO:0005829 TAS
    extracellular exosome GO:0070062 IEA
    Arp2/3 protein complex GO:0005885 IEA
    cell projection GO:0042995 IEA
 Experiment description of studies that identified ARPC4 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ARPC4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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