Gene description for RAB5A
Gene name RAB5A, member RAS oncogene family
Gene symbol RAB5A
Other names/aliases -
Species Bos taurus
 Database cross references - RAB5A
ExoCarta ExoCarta_539764
Entrez Gene 539764
UniProt Q0IIG7  
 RAB5A identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for RAB5A
Molecular Function
    GTPase activity GO:0003924 ISS
    GTP binding GO:0005525 ISS
    GDP binding GO:0019003 ISS
Biological Process
    small GTPase mediated signal transduction GO:0007264 IEA
    endocytosis GO:0006897 ISS
    metabolic process GO:0008152 ISS
    protein transport GO:0015031 IEA
Subcellular Localization
    melanosome GO:0042470 IEA
    cytosol GO:0005829 IEA
    ruffle GO:0001726 IEA
    early endosome membrane GO:0031901 IEA
    clathrin-coated vesicle GO:0030136 IDA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified RAB5A in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RAB5A
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RAB5A is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here