Gene description for LYPLA1
Gene name lysophospholipase I
Gene symbol LYPLA1
Other names/aliases -
Species Bos taurus
 Database cross references - LYPLA1
ExoCarta ExoCarta_539992
Entrez Gene 539992
UniProt Q3MHR0  
 LYPLA1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for LYPLA1
Molecular Function
    palmitoyl-(protein) hydrolase activity GO:0008474 ISS
Biological Process
    fatty acid metabolic process GO:0006631 IEA
    macromolecule depalmitoylation GO:0098734 ISS
Subcellular Localization
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified LYPLA1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for LYPLA1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LYPLA1 is involved
PathwayEvidenceSource
eNOS activation IEA Reactome





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