Gene description for EXOC8
Gene name exocyst complex component 8
Gene symbol EXOC8
Other names/aliases -
Species Bos taurus
 Database cross references - EXOC8
ExoCarta ExoCarta_540237
Entrez Gene 540237
UniProt A4IF89  
 EXOC8 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for EXOC8
Molecular Function
    Ral GTPase binding GO:0017160 IEA
Biological Process
    extracellular matrix disassembly GO:0022617 IEA
    protein transport GO:0015031 IEA
    endosome organization GO:0007032 IEA
    exocyst localization GO:0051601 IBA
    exocyst assembly GO:0001927 IBA
Subcellular Localization
    membrane GO:0016020 IEA
    exocyst GO:0000145 IBA
    growth cone GO:0030426 IEA
    late endosome GO:0005770 IEA
 Experiment description of studies that identified EXOC8 in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for EXOC8
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which EXOC8 is involved
Insulin processing IEA Reactome
Translocation of GLUT4 to the plasma membrane IEA Reactome
VxPx cargo-targeting to cilium IEA Reactome

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