Gene description for SERPINC1
Gene name serpin peptidase inhibitor, clade C (antithrombin), member 1
Gene symbol SERPINC1
Other names/aliases AT3
Species Bos taurus
 Database cross references - SERPINC1
ExoCarta ExoCarta_540261
Entrez Gene 540261
UniProt P41361  
 SERPINC1 identified in exosomes derived from the following tissue/cell type
Serum 19327352    
 Gene ontology annotations for SERPINC1
Molecular Function
    serine-type endopeptidase inhibitor activity GO:0004867 IEA
    heparin binding GO:0008201 IEA
Biological Process
    blood coagulation GO:0007596 IEA
    regulation of blood coagulation, intrinsic pathway GO:2000266 IEA
    negative regulation of endopeptidase activity GO:0010951 IEA
Subcellular Localization
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified SERPINC1 in exosomes
1
Experiment ID 187
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors Ochieng J, Pratap S, Khatua AK, Sakwe AM.
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SERPINC1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SERPINC1 is involved
No pathways found





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