Gene description for MSN
Gene name moesin
Gene symbol MSN
Other names/aliases -
Species Bos taurus
 Database cross references - MSN
ExoCarta ExoCarta_540426
Entrez Gene 540426
UniProt Q2HJ49  
 MSN identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for MSN
Molecular Function
    actin binding GO:0003779 IEA
    double-stranded RNA binding GO:0003725 IEA
    protein kinase binding GO:0019901 IEA
    receptor binding GO:0005102 IEA
    cell adhesion molecule binding GO:0050839 IEA
Biological Process
    positive regulation of gene expression GO:0010628 IEA
    leukocyte cell-cell adhesion GO:0007159 IEA
    leukocyte migration GO:0050900 IEA
    regulation of lymphocyte migration GO:2000401 IEA
    membrane to membrane docking GO:0022614 IEA
    establishment of endothelial barrier GO:0061028 IEA
Subcellular Localization
    basolateral plasma membrane GO:0016323 IEA
    focal adhesion GO:0005925 IEA
    uropod GO:0001931 IEA
    extracellular exosome GO:0070062 IEA
    cytoplasm GO:0005737 IEA
    microvillus membrane GO:0031528 IEA
    extrinsic component of membrane GO:0019898 IEA
    filopodium GO:0030175 IEA
    blood microparticle GO:0072562 IEA
    apical plasma membrane GO:0016324 IEA
    cytoskeleton GO:0005856 IEA
 Experiment description of studies that identified MSN in exosomes
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MSN
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MSN is involved
No pathways found

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