Gene description for NF2
Gene name neurofibromin 2 (merlin)
Gene symbol NF2
Other names/aliases -
Species Bos taurus
 Database cross references - NF2
ExoCarta ExoCarta_540479
Vesiclepedia VP_540479
Entrez Gene 540479
 NF2 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for NF2
Molecular Function
    actin binding GO:0003779 IEA
    cell adhesion molecule binding GO:0050839 IEA
Biological Process
    regulation of cell shape GO:0008360 IEA
    regulation of gliogenesis GO:0014013 IEA
    regulation of organelle assembly GO:1902115 IEA
    positive regulation of protein localization to early endosome GO:1902966 IEA
    positive regulation of early endosome to late endosome transport GO:2000643 IEA
Subcellular Localization
    cytoskeleton GO:0005856 IEA
    plasma membrane GO:0005886 IEA
    adherens junction GO:0005912 IEA
    filopodium GO:0030175 IEA
    apical part of cell GO:0045177 IEA
 Experiment description of studies that identified NF2 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for NF2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which NF2 is involved
No pathways found





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