Gene description for ARPC2
Gene name actin related protein 2/3 complex, subunit 2, 34kDa
Gene symbol ARPC2
Other names/aliases -
Species Bos taurus
 Database cross references - ARPC2
ExoCarta ExoCarta_540838
Entrez Gene 540838
UniProt Q3MHR7  
 ARPC2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ARPC2
Molecular Function
    structural constituent of cytoskeleton GO:0005200 IEA
    actin filament binding GO:0051015 IEA
Biological Process
    positive regulation of substrate adhesion-dependent cell spreading GO:1900026 IEA
    positive regulation of lamellipodium assembly GO:0010592 IEA
    Arp2/3 complex-mediated actin nucleation GO:0034314 IEA
Subcellular Localization
    Golgi apparatus GO:0005794 IEA
    cytosol GO:0005829 TAS
    neuron projection GO:0043005 IEA
    cell leading edge GO:0031252 IEA
    extracellular exosome GO:0070062 IEA
    plasma membrane GO:0005886 IEA
    Arp2/3 protein complex GO:0005885 IEA
    synapse GO:0045202 IEA
    focal adhesion GO:0005925 IEA
    endosome GO:0005768 IEA
 Experiment description of studies that identified ARPC2 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ARPC2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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