Gene description for DNM1L
Gene name dynamin 1-like
Gene symbol DNM1L
Other names/aliases -
Species Bos taurus
 Database cross references - DNM1L
ExoCarta ExoCarta_540892
Vesiclepedia VP_540892
Entrez Gene 540892
UniProt Q2KIA5  
 DNM1L identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for DNM1L
Molecular Function
    GTPase activity GO:0003924 IEA
    GTP binding GO:0005525 IEA
    microtubule binding GO:0008017 IEA
Biological Process
    mitochondrial fission GO:0000266 IEA
    mitochondrial fragmentation involved in apoptotic process GO:0043653 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    mitochondrion GO:0005739 IEA
    microtubule GO:0005874 IEA
    membrane GO:0016020 IEA
 Experiment description of studies that identified DNM1L in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DNM1L
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which DNM1L is involved
PathwayEvidenceSource
Apoptosis IEA Reactome
Apoptotic execution phase IEA Reactome
Programmed Cell Death IEA Reactome





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