Gene description for SEC63
Gene name SEC63 homolog (S. cerevisiae)
Gene symbol SEC63
Other names/aliases -
Species Bos taurus
 Database cross references - SEC63
ExoCarta ExoCarta_541040
Vesiclepedia VP_541040
Entrez Gene 541040
 SEC63 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SEC63
Molecular Function
    RNA binding GO:0003723 IEA
    protein transmembrane transporter activity GO:0008320 IEA
Biological Process
    SRP-dependent cotranslational protein targeting to membrane GO:0006614 IEA
    post-translational protein targeting to endoplasmic reticulum membrane GO:0006620 IEA
Subcellular Localization
    Sec62/Sec63 complex GO:0031207 IEA
 Experiment description of studies that identified SEC63 in sEVs
1
Experiment ID 213
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SEC63
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEC62  
Affinity Capture-Western Bos taurus
2 SEC61G  
Affinity Capture-Western Bos taurus
3 SEC61B  
Affinity Capture-Western Bos taurus
Affinity Capture-Western Bos taurus
4 SEC61A1  
Affinity Capture-Western Bos taurus
View the network image/svg+xml
 Pathways in which SEC63 is involved
No pathways found





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