Gene description for Rabep1
Gene name rabaptin, RAB GTPase binding effector protein 1
Gene symbol Rabep1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Rabep1
ExoCarta ExoCarta_54190
Entrez Gene 54190
UniProt O35550  
 Rabep1 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Rabep1
Molecular Function
    protein homodimerization activity GO:0042803 ISO
    protein binding GO:0005515 IPI
    growth factor activity GO:0008083 IEA
    GTPase activator activity GO:0005096 IEA
Biological Process
    apoptotic process GO:0006915 IEA
    vesicle-mediated transport GO:0016192 ISS
    protein transport GO:0015031 IEA
    endocytosis GO:0006897 IEA
    positive regulation of GTPase activity GO:0043547 IEA
Subcellular Localization
    endosome GO:0005768 ISS
    intracellular membrane-bounded organelle GO:0043231 ISO
    recycling endosome GO:0055037 IEA
    endocytic vesicle GO:0030139 ISS
    early endosome GO:0005769 IEA
 Experiment description of studies that identified Rabep1 in exosomes
1
Experiment ID 97
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Rabep1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Rabep1 is involved
No pathways found





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