Gene description for Aox1
Gene name aldehyde oxidase 1
Gene symbol Aox1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Aox1
ExoCarta ExoCarta_54349
Entrez Gene 54349
UniProt Q9Z0U5  
 Aox1 identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Aox1
Molecular Function
    2 iron, 2 sulfur cluster binding GO:0051537 IEA
    flavin adenine dinucleotide binding GO:0050660 IEA
    electron carrier activity GO:0009055 IEA
    NAD binding GO:0051287 IEA
    aldehyde oxidase activity GO:0004031 ISO
    iron ion binding GO:0005506 IEA
    UDP-N-acetylmuramate dehydrogenase activity GO:0008762 IEA
    molybdopterin cofactor binding GO:0043546 IEA
Biological Process
    oxidation-reduction process GO:0055114 IEA
    xenobiotic metabolic process GO:0006805 TAS
    drug metabolic process GO:0017144 TAS
Subcellular Localization
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 TAS
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Aox1 in exosomes
1
Experiment ID 35
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
CD81|CD63
EV Membrane markers
✔
HSPA5
EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Aox1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Aox1 is involved
No pathways found





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