Gene description for Aox1
Gene name aldehyde oxidase 1
Gene symbol Aox1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Aox1
ExoCarta ExoCarta_54349
Vesiclepedia VP_54349
Entrez Gene 54349
UniProt Q9Z0U5  
 Aox1 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Aox1
Molecular Function
    aldehyde oxidase activity GO:0004031 IBA
    aldehyde oxidase activity GO:0004031 IDA
    aldehyde oxidase activity GO:0004031 IEA
    aldehyde oxidase activity GO:0004031 ISO
    aldehyde oxidase activity GO:0004031 ISS
    iron ion binding GO:0005506 IEA
    iron ion binding GO:0005506 ISO
    iron ion binding GO:0005506 ISS
    oxidoreductase activity GO:0016491 IEA
    identical protein binding GO:0042802 ISO
    protein homodimerization activity GO:0042803 IEA
    protein homodimerization activity GO:0042803 ISO
    protein homodimerization activity GO:0042803 ISS
    molybdopterin cofactor binding GO:0043546 IEA
    molybdopterin cofactor binding GO:0043546 ISO
    molybdopterin cofactor binding GO:0043546 ISS
    flavin adenine dinucleotide binding GO:0050660 ISO
    flavin adenine dinucleotide binding GO:0050660 ISS
    NAD binding GO:0051287 IEA
    2 iron, 2 sulfur cluster binding GO:0051537 IEA
    2 iron, 2 sulfur cluster binding GO:0051537 ISO
    2 iron, 2 sulfur cluster binding GO:0051537 ISS
    FAD binding GO:0071949 IEA
Biological Process
    lipid metabolic process GO:0006629 IEA
    xenobiotic metabolic process GO:0006805 IEA
    xenobiotic metabolic process GO:0006805 ISO
    xenobiotic metabolic process GO:0006805 ISS
    xenobiotic metabolic process GO:0006805 TAS
Subcellular Localization
    cytoplasm GO:0005737 IEA
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    cytosol GO:0005829 ISS
 Experiment description of studies that identified Aox1 in sEVs
1
Experiment ID 35
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|CD81|CD63
Enriched markers
HSPA5
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Aox1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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