Gene description for 6230416C02Rik
Gene name RIKEN cDNA 6230416C02 gene
Gene symbol 6230416C02Rik
Other names/aliases -
Species Mus musculus
 Database cross references - 6230416C02Rik
ExoCarta ExoCarta_545490
Vesiclepedia VP_545490
Entrez Gene 545490
 6230416C02Rik identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for 6230416C02Rik
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA
    DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 IBA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IBA
    regulation of cytokine production GO:0001817 IBA
    regulation of immune system process GO:0002682 IBA
Subcellular Localization
    cellular_component GO:0005575 ND
    nucleoplasm GO:0005654 IBA
 Experiment description of studies that identified 6230416C02Rik in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for 6230416C02Rik
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which 6230416C02Rik is involved
No pathways found





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