Gene description for FAM20A
Gene name family with sequence similarity 20, member A
Gene symbol FAM20A
Other names/aliases AI1G
AIGFS
FP2747
Species Homo sapiens
 Database cross references - FAM20A
ExoCarta ExoCarta_54757
Vesiclepedia VP_54757
Entrez Gene 54757
HGNC 23015
MIM 611062
UniProt Q96MK3  
 FAM20A identified in sEVs derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for FAM20A
Molecular Function
    protein serine/threonine kinase activity GO:0004674 IDA
    protein binding GO:0005515 IPI
    phosphotransferase activity, alcohol group as acceptor GO:0016773 IBA
    protein serine/threonine kinase activator activity GO:0043539 IBA
    protein serine/threonine kinase activator activity GO:0043539 IDA
Biological Process
    positive regulation of protein phosphorylation GO:0001934 IDA
    positive regulation of protein phosphorylation GO:0001934 ISS
    response to bacterium GO:0009617 IEA
    biomineral tissue development GO:0031214 IMP
    tooth eruption GO:0044691 IMP
    calcium ion homeostasis GO:0055074 IMP
    enamel mineralization GO:0070166 IBA
    enamel mineralization GO:0070166 IMP
Subcellular Localization
    extracellular space GO:0005615 IDA
    cytoplasm GO:0005737 ISS
    endoplasmic reticulum GO:0005783 ISS
    Golgi apparatus GO:0005794 IBA
    Golgi apparatus GO:0005794 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified FAM20A in sEVs
1
Experiment ID 66
MISEV standards
IEM
Biophysical techniques
TSG101|Alix|CD63|CD81
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for FAM20A
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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