Gene description for THNSL2
Gene name threonine synthase-like 2 (S. cerevisiae)
Gene symbol THNSL2
Other names/aliases SOFAT
THS2
TSH2
Species Homo sapiens
 Database cross references - THNSL2
ExoCarta ExoCarta_55258
Entrez Gene 55258
HGNC 25602
MIM 611261
UniProt Q86YJ6  
 THNSL2 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for THNSL2
Molecular Function
    pyridoxal phosphate binding GO:0030170 ISS
    threonine synthase activity GO:0004795 IBA
    serine binding GO:0070905 ISS
    cytokine activity GO:0005125 IEA
    molecular_function GO:0003674 ND
Biological Process
    serine family amino acid catabolic process GO:0009071 ISS
    2-oxobutyrate biosynthetic process GO:0046360 ISS
    dephosphorylation GO:0016311 ISS
    threonine biosynthetic process GO:0009088 IBA
    biological_process GO:0008150 ND
Subcellular Localization
    cellular_component GO:0005575 ND
    cytoplasm GO:0005737 IBA
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified THNSL2 in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for THNSL2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZBTB16  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which THNSL2 is involved
No pathways found





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