Gene description for THNSL2
Gene name threonine synthase-like 2 (S. cerevisiae)
Gene symbol THNSL2
Other names/aliases SOFAT
THS2
TSH2
Species Homo sapiens
 Database cross references - THNSL2
ExoCarta ExoCarta_55258
Vesiclepedia VP_55258
Entrez Gene 55258
HGNC 25602
MIM 611261
UniProt Q86YJ6  
 THNSL2 identified in sEVs derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for THNSL2
Molecular Function
    threonine synthase activity GO:0004795 IBA
    cytokine activity GO:0005125 IEA
    pyridoxal phosphate binding GO:0030170 IBA
    pyridoxal phosphate binding GO:0030170 ISS
    serine binding GO:0070905 ISS
Biological Process
    signal transduction GO:0007165 IEA
    serine family amino acid catabolic process GO:0009071 IBA
    serine family amino acid catabolic process GO:0009071 ISS
    dephosphorylation GO:0016311 ISS
    2-oxobutyrate biosynthetic process GO:0046360 IBA
    2-oxobutyrate biosynthetic process GO:0046360 ISS
Subcellular Localization
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified THNSL2 in sEVs
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for THNSL2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZBTB16  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which THNSL2 is involved
No pathways found





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