Gene description for H2AFJ
Gene name H2A histone family, member J
Gene symbol H2AFJ
Other names/aliases H2AJ
Species Homo sapiens
 Database cross references - H2AFJ
ExoCarta ExoCarta_55766
Vesiclepedia VP_55766
Entrez Gene 55766
HGNC 14456
UniProt Q9BTM1  
 H2AFJ identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Colorectal cancer cells 19837982    
Neuroblastoma cells 25944692    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for H2AFJ
Molecular Function
    DNA binding GO:0003677 IEA
    structural constituent of chromatin GO:0030527 IBA
    protein heterodimerization activity GO:0046982 IEA
Biological Process
    spermatogenesis GO:0007283 IEA
    cerebral cortex development GO:0021987 IEA
    heterochromatin formation GO:0031507 IBA
    cellular response to gamma radiation GO:0071480 IEA
    cellular senescence GO:0090398 IEA
Subcellular Localization
    nucleosome GO:0000786 IBA
    nucleus GO:0005634 IBA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified H2AFJ in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 21
MISEV standards
EM|IEM
Biophysical techniques
Alix|TSG101|HSP70|CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
6
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
7
Experiment ID 138
MISEV standards
EM
Biophysical techniques
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
HSP90B1
Negative markers
Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
8
Experiment ID 140
MISEV standards
EM
Biophysical techniques
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
HSP90B1
Negative markers
Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
9
Experiment ID 141
MISEV standards
EM
Biophysical techniques
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
HSP90B1
Negative markers
Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
10
Experiment ID 142
MISEV standards
EM
Biophysical techniques
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
HSP90B1
Negative markers
Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name LNCaP - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
11
Experiment ID 144
MISEV standards
EM
Biophysical techniques
HSP70|HSP90|RAB5|CD9
Enriched markers
HSP90B1
Negative markers
Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
12
Experiment ID 145
MISEV standards
EM
Biophysical techniques
HSP70|HSP90|RAB5|CD10
Enriched markers
HSP90B1
Negative markers
Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
13
Experiment ID 146
MISEV standards
EM
Biophysical techniques
HSP70|HSP90|CD9
Enriched markers
HSP90B1
Negative markers
Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name RWPE - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
14
Experiment ID 274
MISEV standards
EM
Biophysical techniques
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
AIF
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
15
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for H2AFJ
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SLFN11 91607
Affinity Capture-MS Homo sapiens
2 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
3 RBMXL1  
Affinity Capture-MS Homo sapiens
4 UTP11L  
Affinity Capture-MS Homo sapiens
5 PRPF38A 84950
Affinity Capture-MS Homo sapiens
6 HIST1H2BJ 8970
Cross-Linking-MS (XL-MS) Homo sapiens
7 ESF1 51575
Affinity Capture-MS Homo sapiens
8 C9orf78 51759
Affinity Capture-MS Homo sapiens
9 HIST1H2BB 3018
Cross-Linking-MS (XL-MS) Homo sapiens
10 RBBP6 5930
Affinity Capture-MS Homo sapiens
11 HIST3H2BB 128312
Cross-Linking-MS (XL-MS) Homo sapiens
12 PNMAL1  
Affinity Capture-MS Homo sapiens
13 BUD13  
Affinity Capture-MS Homo sapiens
14 CWC25 54883
Affinity Capture-MS Homo sapiens
15 PRPF40A 55660
Affinity Capture-MS Homo sapiens
16 USP36  
Affinity Capture-MS Homo sapiens
17 TCEB3 6924
Affinity Capture-MS Homo sapiens
18 PTDSS2 81490
Affinity Capture-MS Homo sapiens
19 HIST3H2A 92815
Cross-Linking-MS (XL-MS) Homo sapiens
20 MCM2 4171
Affinity Capture-MS Homo sapiens
21 PRPF38B 55119
Affinity Capture-MS Homo sapiens
22 TONSL  
Affinity Capture-MS Homo sapiens
23 HIST2H3A 333932
Cross-Linking-MS (XL-MS) Homo sapiens
24 CDK12 51755
Affinity Capture-MS Homo sapiens
25 ZGPAT  
Affinity Capture-MS Homo sapiens
26 MED27  
Affinity Capture-MS Homo sapiens
27 HIST2H2AC 8338
Cross-Linking-MS (XL-MS) Homo sapiens
28 HIST1H2AA 221613
Cross-Linking-MS (XL-MS) Homo sapiens
29 YY1AP1 55249
Affinity Capture-MS Homo sapiens
30 RRP7A 27341
Affinity Capture-MS Homo sapiens
31 CXXC1  
Affinity Capture-MS Homo sapiens
32 ING4  
Affinity Capture-MS Homo sapiens
33 HIST2H2AB 317772
Cross-Linking-MS (XL-MS) Homo sapiens
34 HIST1H4A 8359
Cross-Linking-MS (XL-MS) Homo sapiens
35 PINX1  
Affinity Capture-MS Homo sapiens
36 FAM204A  
Affinity Capture-MS Homo sapiens
37 RTF1 23168
Affinity Capture-MS Homo sapiens
38 ZCCHC17  
Affinity Capture-MS Homo sapiens
39 VCP 7415
Affinity Capture-MS Homo sapiens
40 U2AF2 11338
Affinity Capture-MS Homo sapiens
41 SNRNP27  
Affinity Capture-MS Homo sapiens
42 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
43 H2AFY 9555
Cross-Linking-MS (XL-MS) Homo sapiens
44 PPM1G 5496
Affinity Capture-MS Homo sapiens
45 KIF20B  
Affinity Capture-MS Homo sapiens
46 RAD21 5885
Affinity Capture-Western Homo sapiens
47 H3F3C 440093
Cross-Linking-MS (XL-MS) Homo sapiens
48 IPO9 55705
Affinity Capture-MS Homo sapiens
49 WDR46  
Affinity Capture-MS Homo sapiens
50 HNRNPD 3184
Affinity Capture-MS Homo sapiens
51 MIER3 166968
Affinity Capture-MS Homo sapiens
52 MIER1  
Affinity Capture-MS Homo sapiens
53 HIST1H3A 8350
Cross-Linking-MS (XL-MS) Homo sapiens
54 C11orf57  
Affinity Capture-MS Homo sapiens
55 DHX36 170506
Affinity Capture-MS Homo sapiens
56 PINK1  
Affinity Capture-MS Homo sapiens
57 DNAJC2 27000
Affinity Capture-MS Homo sapiens
58 HIST2H2BF 440689
Cross-Linking-MS (XL-MS) Homo sapiens
59 DCAF13 25879
Affinity Capture-MS Homo sapiens
60 H1F0 3005
Affinity Capture-MS Homo sapiens
61 RBM27  
Affinity Capture-MS Homo sapiens
62 HIST3H3 8290
Cross-Linking-MS (XL-MS) Homo sapiens
63 HIST1H2BO 8348
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
64 RP9  
Affinity Capture-MS Homo sapiens
65 LENG1  
Affinity Capture-MS Homo sapiens
66 TJP2 9414
Affinity Capture-MS Homo sapiens
67 RBM14-RBM4 100526737
Affinity Capture-MS Homo sapiens
68 MAP9 79884
Affinity Capture-MS Homo sapiens
69 CRAMP1L 57585
Affinity Capture-MS Homo sapiens
70 MMS22L  
Affinity Capture-MS Homo sapiens
71 DIDO1  
Affinity Capture-MS Homo sapiens
72 CACTIN  
Affinity Capture-MS Homo sapiens
73 ARGLU1  
Affinity Capture-MS Homo sapiens
74 SUPT16H 11198
Affinity Capture-MS Homo sapiens
75 DDX46 9879
Affinity Capture-MS Homo sapiens
76 RRP36 88745
Affinity Capture-MS Homo sapiens
77 PRRC2A 7916
Affinity Capture-MS Homo sapiens
78 PARP1 142
Affinity Capture-MS Homo sapiens
79 H3F3A 3020
Cross-Linking-MS (XL-MS) Homo sapiens
80 RBM25 58517
Affinity Capture-MS Homo sapiens
81 NOL10  
Affinity Capture-MS Homo sapiens
82 WBP11  
Affinity Capture-MS Homo sapiens
83 MCM5 4174
Affinity Capture-MS Homo sapiens
84 PHF3  
Affinity Capture-MS Homo sapiens
85 Rbm8a  
Affinity Capture-MS Mus musculus
86 KNOP1 400506
Affinity Capture-MS Homo sapiens
87 NPAT  
Affinity Capture-MS Homo sapiens
88 HIST1H2BN 8341
Cross-Linking-MS (XL-MS) Homo sapiens
89 GON4L  
Affinity Capture-MS Homo sapiens
90 LOC102724334 102724334
Cross-Linking-MS (XL-MS) Homo sapiens
91 TRIP12 9320
Affinity Capture-MS Homo sapiens
92 DNTTIP2  
Affinity Capture-MS Homo sapiens
93 SFSWAP  
Affinity Capture-MS Homo sapiens
94 SNIP1  
Affinity Capture-MS Homo sapiens
95 RIOK2 55781
Affinity Capture-MS Homo sapiens
96 HNRNPLL 92906
Affinity Capture-MS Homo sapiens
97 HSF1  
Affinity Capture-MS Homo sapiens
98 CBX8 57332
Affinity Capture-MS Homo sapiens
99 TMEM109 79073
Cross-Linking-MS (XL-MS) Homo sapiens
100 HABP4  
Affinity Capture-MS Homo sapiens
101 SERBP1 26135
Affinity Capture-MS Homo sapiens
102 C9orf72  
Affinity Capture-MS Homo sapiens
103 AR 367
Affinity Capture-MS Homo sapiens
104 SSRP1 6749
Affinity Capture-MS Homo sapiens
105 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
106 ESCO2  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which H2AFJ is involved
PathwayEvidenceSource
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 TAS Reactome
Activation of anterior HOX genes in hindbrain development during early embryogenesis IEA Reactome
Activation of HOX genes during differentiation IEA Reactome
Assembly of the ORC complex at the origin of replication TAS Reactome
Assembly of the pre-replicative complex TAS Reactome
B-WICH complex positively regulates rRNA expression TAS Reactome
Base Excision Repair TAS Reactome
Base Excision Repair IEA Reactome
Base-Excision Repair, AP Site Formation TAS Reactome
Base-Excision Repair, AP Site Formation IEA Reactome
Cell Cycle TAS Reactome
Cell Cycle IEA Reactome
Cell Cycle, Mitotic TAS Reactome
Cellular responses to stimuli TAS Reactome
Cellular responses to stress TAS Reactome
Cellular Senescence TAS Reactome
Chromatin modifications during the maternal to zygotic transition (MZT) IEA Reactome
Chromatin modifying enzymes TAS Reactome
Chromatin organization TAS Reactome
Chromosome Maintenance TAS Reactome
Cleavage of the damaged purine TAS Reactome
Cleavage of the damaged purine IEA Reactome
Cleavage of the damaged pyrimidine IEA Reactome
Condensation of Prophase Chromosomes TAS Reactome
Defective pyroptosis TAS Reactome
Deposition of new CENPA-containing nucleosomes at the centromere TAS Reactome
Depurination TAS Reactome
Depurination IEA Reactome
Depyrimidination IEA Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Diseases of programmed cell death TAS Reactome
DNA Damage/Telomere Stress Induced Senescence TAS Reactome
DNA methylation IEA Reactome
DNA Repair TAS Reactome
DNA Repair IEA Reactome
DNA Replication TAS Reactome
DNA Replication Pre-Initiation TAS Reactome
Epigenetic regulation by WDR5-containing histone modifying complexes IEA Reactome
Epigenetic regulation by WDR5-containing histone modifying complexes TAS Reactome
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes IEA Reactome
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes TAS Reactome
Epigenetic regulation of gene expression TAS Reactome
Epigenetic regulation of gene expression IEA Reactome
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes IEA Reactome
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes TAS Reactome
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression IEA Reactome
ESR-mediated signaling TAS Reactome
Estrogen-dependent gene expression TAS Reactome
Formation of the beta-catenin:TCF transactivating complex IEA Reactome
Formation of the beta-catenin:TCF transactivating complex TAS Reactome
Gene expression (Transcription) TAS Reactome
Gene expression (Transcription) IEA Reactome
Gene Silencing by RNA TAS Reactome
Generic Transcription Pathway TAS Reactome
Generic Transcription Pathway IEA Reactome
Inhibition of DNA recombination at telomere TAS Reactome
M Phase TAS Reactome
Maternal to zygotic transition (MZT) IEA Reactome
Meiosis IEA Reactome
Meiotic recombination IEA Reactome
Meiotic synapsis IEA Reactome
Mitotic Prophase TAS Reactome
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis IEA Reactome
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis TAS Reactome
Negative epigenetic regulation of rRNA expression TAS Reactome
Negative epigenetic regulation of rRNA expression IEA Reactome
NoRC negatively regulates rRNA expression TAS Reactome
NoRC negatively regulates rRNA expression IEA Reactome
Nucleosome assembly TAS Reactome
Oxidative Stress Induced Senescence TAS Reactome
Packaging Of Telomere Ends TAS Reactome
Positive epigenetic regulation of rRNA expression TAS Reactome
Positive epigenetic regulation of rRNA expression IEA Reactome
PRC2 methylates histones and DNA TAS Reactome
Pre-NOTCH Expression and Processing IEA Reactome
Pre-NOTCH Transcription and Translation IEA Reactome
Recognition and association of DNA glycosylase with site containing an affected purine TAS Reactome
Recognition and association of DNA glycosylase with site containing an affected purine IEA Reactome
Recognition and association of DNA glycosylase with site containing an affected pyrimidine IEA Reactome
Regulation of endogenous retroelements TAS Reactome
Regulation of endogenous retroelements IEA Reactome
Regulation of endogenous retroelements by KRAB-ZFP proteins TAS Reactome
Regulation of endogenous retroelements by KRAB-ZFP proteins IEA Reactome
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) IEA Reactome
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex TAS Reactome
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex IEA Reactome
Reproduction IEA Reactome
RHO GTPase Effectors TAS Reactome
RHO GTPases activate PKNs TAS Reactome
RMTs methylate histone arginines TAS Reactome
RNA Polymerase I Promoter Clearance TAS Reactome
RNA Polymerase I Promoter Escape TAS Reactome
RNA Polymerase I Promoter Opening TAS Reactome
RNA Polymerase I Transcription TAS Reactome
RNA Polymerase II Transcription TAS Reactome
RNA Polymerase II Transcription IEA Reactome
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function TAS Reactome
RUNX1 regulates transcription of genes involved in differentiation of HSCs IEA Reactome
Senescence-Associated Secretory Phenotype (SASP) TAS Reactome
Signal Transduction TAS Reactome
Signal Transduction IEA Reactome
Signaling by NOTCH IEA Reactome
Signaling by Nuclear Receptors TAS Reactome
Signaling by Rho GTPases TAS Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 TAS Reactome
Signaling by WNT IEA Reactome
Signaling by WNT TAS Reactome
SIRT1 negatively regulates rRNA expression TAS Reactome
TCF dependent signaling in response to WNT IEA Reactome
TCF dependent signaling in response to WNT TAS Reactome
Telomere Maintenance TAS Reactome
Transcriptional regulation by RUNX1 TAS Reactome
Transcriptional regulation by RUNX1 IEA Reactome
Transcriptional regulation by small RNAs TAS Reactome
Transcriptional regulation of granulopoiesis IEA Reactome





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