Gene description for THSD1
Gene name thrombospondin, type I, domain containing 1
Gene symbol THSD1
Other names/aliases TMTSP
UNQ3010
Species Homo sapiens
 Database cross references - THSD1
ExoCarta ExoCarta_55901
Entrez Gene 55901
HGNC 17754
UniProt Q9NS62  
 THSD1 identified in exosomes derived from the following tissue/cell type
Keratinocytes 19530224    
Keratinocytes 19530224    
 Gene ontology annotations for THSD1
Biological Process
    hematopoietic progenitor cell differentiation GO:0002244 IEA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    cell surface GO:0009986 IEA
    extracellular region GO:0005576 IEA
    integral component of membrane GO:0016021 IEA
    cell periphery GO:0071944 IEA
 Experiment description of studies that identified THSD1 in exosomes
1
Experiment ID 189
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors Chavez-Muñoz C, Kilani RT, Ghahary A.
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 190
ISEV standards
✔
EM
EV Biophysical techniques
✔
HSC70
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors Chavez-Muñoz C, Kilani RT, Ghahary A.
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for THSD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which THSD1 is involved
PathwayEvidenceSource
O-glycosylation of TSR domain-containing proteins TAS Reactome





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