Gene description for THSD1
Gene name thrombospondin, type I, domain containing 1
Gene symbol THSD1
Other names/aliases TMTSP
UNQ3010
Species Homo sapiens
 Database cross references - THSD1
ExoCarta ExoCarta_55901
Vesiclepedia VP_55901
Entrez Gene 55901
HGNC 17754
UniProt Q9NS62  
 THSD1 identified in sEVs derived from the following tissue/cell type
Keratinocytes 19530224    
Keratinocytes 19530224    
 Gene ontology annotations for THSD1
Molecular Function
    protein binding GO:0005515 IPI
    extracellular matrix binding GO:0050840 IMP
Biological Process
    focal adhesion assembly GO:0048041 IDA
Subcellular Localization
    extracellular region GO:0005576 IEA
    endosome GO:0005768 IDA
    cytosol GO:0005829 IDA
    focal adhesion GO:0005925 IMP
    endosome membrane GO:0010008 IEA
    cell periphery GO:0071944 IBA
 Experiment description of studies that identified THSD1 in sEVs
1
Experiment ID 189
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 190
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for THSD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RAB11A 8766
Proximity Label-MS Homo sapiens
2 GJA1 2697
Proximity Label-MS Homo sapiens
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