Gene description for Apom
Gene name apolipoprotein M
Gene symbol Apom
Other names/aliases 1190010O19Rik
G3a
NG20
Species Mus musculus
 Database cross references - Apom
ExoCarta ExoCarta_55938
Vesiclepedia VP_55938
Entrez Gene 55938
UniProt Q9Z1R3  
 Apom identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Apom
Molecular Function
    lipid transporter activity GO:0005319 IBA
    lipid transporter activity GO:0005319 IEA
    lipid transporter activity GO:0005319 ISO
    protein binding GO:0005515 IPI
    phospholipid binding GO:0005543 IBA
    phospholipid binding GO:0005543 ISO
    phospholipid binding GO:0005543 ISS
    antioxidant activity GO:0016209 IDA
    antioxidant activity GO:0016209 ISO
Biological Process
    cholesterol efflux GO:0033344 IBA
    cholesterol efflux GO:0033344 IMP
    cholesterol efflux GO:0033344 ISO
    high-density lipoprotein particle remodeling GO:0034375 IBA
    high-density lipoprotein particle remodeling GO:0034375 IMP
    high-density lipoprotein particle remodeling GO:0034375 ISO
    high-density lipoprotein particle assembly GO:0034380 IBA
    high-density lipoprotein particle assembly GO:0034380 IMP
    high-density lipoprotein particle clearance GO:0034384 IBA
    high-density lipoprotein particle clearance GO:0034384 IMP
    negative regulation of plasma lipoprotein oxidation GO:0034445 IDA
    negative regulation of plasma lipoprotein oxidation GO:0034445 ISO
    lipoprotein metabolic process GO:0042157 IMP
    reverse cholesterol transport GO:0043691 IMP
    cellular oxidant detoxification GO:0098869 IEA
Subcellular Localization
    extracellular region GO:0005576 IDA
    extracellular space GO:0005615 ISO
    very-low-density lipoprotein particle GO:0034361 IBA
    very-low-density lipoprotein particle GO:0034361 IEA
    very-low-density lipoprotein particle GO:0034361 ISO
    low-density lipoprotein particle GO:0034362 IBA
    low-density lipoprotein particle GO:0034362 IEA
    low-density lipoprotein particle GO:0034362 ISO
    high-density lipoprotein particle GO:0034364 IBA
    high-density lipoprotein particle GO:0034364 IDA
    high-density lipoprotein particle GO:0034364 ISO
    discoidal high-density lipoprotein particle GO:0034365 IDA
    discoidal high-density lipoprotein particle GO:0034365 ISO
    spherical high-density lipoprotein particle GO:0034366 IEA
    spherical high-density lipoprotein particle GO:0034366 ISO
 Experiment description of studies that identified Apom in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Apom
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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