ExoCarta: Gene summary

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Gene description for Rplp1
Gene name	ribosomal protein, large, P1
Gene symbol	Rplp1
Other names/aliases	2410042H16Rik Arpp1 C430017H15Rik
Species	Mus musculus
Database cross references - Rplp1
ExoCarta	ExoCarta_56040
Entrez Gene	56040
UniProt	P47955
Rplp1 identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Rplp1

Molecular Function
	molecular_function	GO:0003674	ND
	structural constituent of ribosome	GO:0003735	IEA
Biological Process
	translational elongation	GO:0006414	IEA
	regulation of translation	GO:0006417	IMP
Subcellular Localization
	ribosome	GO:0005840	IEA
	ribonucleoprotein complex	GO:0030529	IEA
	intracellular	GO:0005622	IEA

Experiment description of studies that identified Rplp1 in exosomes

Experiment ID

ISEV standards
✔ EM	EV Biophysical techniques
✘	EV Cytosolic markers
✔ CD63	EV Membrane markers
✘	EV Negative markers
✘	EV Particle analysis

Identified molecule

protein

Identification method

Mass spectrometry

PubMed ID

17486113

Organism

Mus musculus
Homo sapiens

Experiment description

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.

Authors

Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO

Journal name

NCB

Publication year

2007

Sample

Mast cells

Sample name

MC9
Bone marrow-derived mast cells
HMC-1

Isolation/purification methods

Filtration
Ultracentrifugation
Sucrose density gradient

Flotation density

1.11-1.21 g/mL

Molecules identified in the study

Protein
mRNA
miRNA

Methods used in the study

Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array