Gene description for Stk3
Gene name	serine/threonine kinase 3
Gene symbol	Stk3
Other names/aliases	0610042I06Rik MST Mst2 Mst3 Ste20 mess1
Species	Mus musculus
Database cross references - Stk3
ExoCarta	ExoCarta_56274
Entrez Gene	56274
UniProt	Q9JI10
Stk3 identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Stk3

Molecular Function     protein kinase activity GO:0004672 IEA     protein serine/threonine kinase activity GO:0004674 ISO     ATP binding GO:0005524 ISO     metal ion binding GO:0046872 IEA     transferase activity, transferring phosphorus-containing groups GO:0016772 IEA     kinase activity GO:0016301 IEA     nucleotide binding GO:0000166 IEA     MAP kinase kinase kinase activity GO:0004709 IBA     transferase activity GO:0016740 IEA     magnesium ion binding GO:0000287 ISO Biological Process     regulation of cell differentiation involved in embryonic placenta development GO:0060800 IGI     neural tube formation GO:0001841 IGI     positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 IGI     negative regulation of cell proliferation GO:0008285 IGI     intracellular signal transduction GO:0035556 ISO     cell differentiation involved in embryonic placenta development GO:0060706 IGI     central nervous system development GO:0007417 IGI     endocardium development GO:0003157 IGI     negative regulation of organ growth GO:0046621 IGI     positive regulation of apoptotic process GO:0043065 IGI     apoptotic process GO:0006915 IEA     positive regulation of protein kinase B signaling GO:0051897 IGI     phosphorylation GO:0016310 IEA     hippo signaling GO:0035329 ISO     regulation of mitotic cell cycle GO:0007346 IBA     protein stabilization GO:0050821 ISO     activation of MAPKK activity GO:0000186 IBA     stress-activated protein kinase signaling cascade GO:0031098 IBA     positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 ISO     positive regulation of fat cell differentiation GO:0045600 IGI     protein phosphorylation GO:0006468 ISO     positive regulation of protein binding GO:0032092 ISO     MAPK cascade GO:0000165 IBA     primitive hemopoiesis GO:0060215 IGI     signal transduction GO:0007165 IEA     negative regulation of canonical Wnt signaling pathway GO:0090090 ISO     positive regulation of JNK cascade GO:0046330 IGI     signal transduction by protein phosphorylation GO:0023014 IBA     hepatocyte apoptotic process GO:0097284 IGI Subcellular Localization     nucleus GO:0005634 IBA     cytoplasm GO:0005737 ISO     intracellular GO:0005622 IMP