Gene description for SLC7A10
Gene name solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
Gene symbol SLC7A10
Other names/aliases ASC1
HASC-1
asc-1
Species Homo sapiens
 Database cross references - SLC7A10
ExoCarta ExoCarta_56301
Entrez Gene 56301
HGNC 11058
MIM 607959
UniProt Q9NS82  
 SLC7A10 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for SLC7A10
Molecular Function
    L-serine transmembrane transporter activity GO:0015194 TAS
    neutral amino acid transmembrane transporter activity GO:0015175 IDA
Biological Process
    ion transport GO:0006811 TAS
    leukocyte migration GO:0050900 TAS
    D-serine transport GO:0042942 IEA
    amino acid transmembrane transport GO:0003333 IEA
    amino acid transport GO:0006865 TAS
    D-alanine transport GO:0042941 IEA
    L-serine transport GO:0015825 TAS
    transmembrane transport GO:0055085 TAS
    neutral amino acid transport GO:0015804 IDA
    blood coagulation GO:0007596 TAS
Subcellular Localization
    plasma membrane GO:0005886 TAS
    integral component of plasma membrane GO:0005887 NAS
    membrane GO:0016020 TAS
 Experiment description of studies that identified SLC7A10 in exosomes
1
Experiment ID 126
ISEV standards
✘ EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for SLC7A10
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SLC3A2 6520
Invivo Homo sapiens
View the network image/svg+xml
 Pathways in which SLC7A10 is involved
PathwayEvidenceSource
Amino acid transport across the plasma membrane TAS Reactome
Basigin interactions TAS Reactome





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