Gene description for Morf4l2
Gene name mortality factor 4 like 2
Gene symbol Morf4l2
Other names/aliases 2410017O14Rik
Mrgx
Sid393p
mKIAA0026
Species Mus musculus
 Database cross references - Morf4l2
ExoCarta ExoCarta_56397
Entrez Gene 56397
UniProt Q9R0Q4  
 Morf4l2 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Morf4l2
Biological Process
    chromatin modification GO:0016568 IEA
    regulation of growth GO:0040008 IEA
    cellular response to DNA damage stimulus GO:0006974 IEA
    transcription, DNA-templated GO:0006351 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
    DNA repair GO:0006281 IEA
Subcellular Localization
    nucleolus GO:0005730 ISO
    nucleoplasm GO:0005654 ISO
    nucleus GO:0005634 IEA
 Experiment description of studies that identified Morf4l2 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Morf4l2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Morf4l2 is involved
PathwayEvidenceSource
HATs acetylate histones IEA Reactome





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