Gene description for Aldh18a1
Gene name aldehyde dehydrogenase 18 family, member A1
Gene symbol Aldh18a1
Other names/aliases 2810433K04Rik
AI429789
Pycs
Species Mus musculus
 Database cross references - Aldh18a1
ExoCarta ExoCarta_56454
Entrez Gene 56454
UniProt Q9Z110  
 Aldh18a1 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Aldh18a1
Molecular Function
    oxidoreductase activity GO:0016491 IEA
    oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 IEA
    transferase activity GO:0016740 IEA
    poly(A) RNA binding GO:0044822 ISO
    kinase activity GO:0016301 IEA
    ATP binding GO:0005524 IEA
    glutamate 5-kinase activity GO:0004349 ISO
    catalytic activity GO:0003824 IEA
    glutamate-5-semialdehyde dehydrogenase activity GO:0004350 ISO
    nucleotide binding GO:0000166 IEA
Biological Process
    proline biosynthetic process GO:0006561 ISO
    cellular amino acid biosynthetic process GO:0008652 TAS
    citrulline biosynthetic process GO:0019240 ISO
    oxidation-reduction process GO:0055114 IBA
    phosphorylation GO:0016310 ISO
    ornithine biosynthetic process GO:0006592 ISO
    glutamate metabolic process GO:0006536 ISO
    metabolic process GO:0008152 IEA
Subcellular Localization
    mitochondrion GO:0005739 ISO
    cytoplasm GO:0005737 ISO
    mitochondrial inner membrane GO:0005743 IEA
    membrane GO:0016020 IEA
 Experiment description of studies that identified Aldh18a1 in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Aldh18a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Aldh18a1 is involved
PathwayEvidenceSource
Amino acid synthesis and interconversion (transamination) IEA Reactome





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