Gene description for Aldh18a1
Gene name aldehyde dehydrogenase 18 family, member A1
Gene symbol Aldh18a1
Other names/aliases 2810433K04Rik
AI429789
Pycs
Species Mus musculus
 Database cross references - Aldh18a1
ExoCarta ExoCarta_56454
Vesiclepedia VP_56454
Entrez Gene 56454
UniProt Q9Z110  
 Aldh18a1 identified in sEVs derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Aldh18a1
Molecular Function
    glutamate 5-kinase activity GO:0004349 IDA
    glutamate 5-kinase activity GO:0004349 ISO
    glutamate-5-semialdehyde dehydrogenase activity GO:0004350 IBA
    glutamate-5-semialdehyde dehydrogenase activity GO:0004350 ISO
    glutamate-5-semialdehyde dehydrogenase activity GO:0004350 ISS
    ATP binding GO:0005524 IEA
    identical protein binding GO:0042802 IEA
    identical protein binding GO:0042802 ISO
Biological Process
    glutamate metabolic process GO:0006536 ISO
    glutamate metabolic process GO:0006536 ISS
    proline biosynthetic process GO:0006561 ISO
    proline biosynthetic process GO:0006561 ISS
    ornithine biosynthetic process GO:0006592 IEA
    ornithine biosynthetic process GO:0006592 ISO
    amino acid biosynthetic process GO:0008652 TAS
    response to temperature stimulus GO:0009266 IEA
    response to temperature stimulus GO:0009266 ISO
    citrulline biosynthetic process GO:0019240 ISO
    citrulline biosynthetic process GO:0019240 ISS
    L-proline biosynthetic process GO:0055129 IEA
Subcellular Localization
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 ISO
    mitochondrial inner membrane GO:0005743 IEA
    mitochondrial matrix GO:0005759 IEA
    mitochondrial membrane GO:0031966 ISO
 Experiment description of studies that identified Aldh18a1 in sEVs
1
Experiment ID 188
MISEV standards
EM
Biophysical techniques
GAPDH|UCHL1|HSP90
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors "Lee HS, Jeong J, Lee KJ."
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Aldh18a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Eed  
Affinity Capture-MS Mus musculus
2 Mettl21e  
Affinity Capture-MS Mus musculus
View the network image/svg+xml



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