Gene description for Pigo
Gene name phosphatidylinositol glycan anchor biosynthesis, class O
Gene symbol Pigo
Other names/aliases PIG-O
Species Mus musculus
 Database cross references - Pigo
ExoCarta ExoCarta_56703
Entrez Gene 56703
 Pigo identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Pigo
Molecular Function
    catalytic activity GO:0003824 IEA
    protein binding GO:0005515 IPI
    mannose-ethanolamine phosphotransferase activity GO:0051377 IBA
    transferase activity GO:0016740 IEA
    phosphotransferase activity, for other substituted phosphate groups GO:0016780 TAS
    Kdo transferase activity GO:0043842 IEA
Biological Process
    GPI anchor biosynthetic process GO:0006506 IDA
    metabolic process GO:0008152 IEA
Subcellular Localization
    membrane GO:0016020 ISO
    integral component of membrane GO:0016021 IEA
    endoplasmic reticulum GO:0005783 IEA
    endoplasmic reticulum membrane GO:0005789 IDA
 Experiment description of studies that identified Pigo in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Pigo
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pigo is involved
No pathways found





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