Gene description for Pigo
Gene name phosphatidylinositol glycan anchor biosynthesis, class O
Gene symbol Pigo
Other names/aliases PIG-O
Species Mus musculus
 Database cross references - Pigo
ExoCarta ExoCarta_56703
Vesiclepedia VP_56703
Entrez Gene 56703
 Pigo identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Pigo
Molecular Function
    protein binding GO:0005515 IPI
    phosphotransferase activity, for other substituted phosphate groups GO:0016780 TAS
    mannose-ethanolamine phosphotransferase activity GO:0051377 IBA
    mannose-ethanolamine phosphotransferase activity GO:0051377 IEA
    mannose-ethanolamine phosphotransferase activity GO:0051377 ISO
Biological Process
    GPI anchor biosynthetic process GO:0006506 IBA
    GPI anchor biosynthetic process GO:0006506 IDA
    GPI anchor biosynthetic process GO:0006506 IEA
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IBA
    endoplasmic reticulum membrane GO:0005789 IDA
    endoplasmic reticulum membrane GO:0005789 TAS
 Experiment description of studies that identified Pigo in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Pigo
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Pigf  
Affinity Capture-Western Mus musculus
View the network image/svg+xml
 Pathways in which Pigo is involved
No pathways found





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