Gene description for C1qtnf1
Gene name C1q and tumor necrosis factor related protein 1
Gene symbol C1qtnf1
Other names/aliases 1600017K21Rik
CTRP1
Zsig37
Species Mus musculus
 Database cross references - C1qtnf1
ExoCarta ExoCarta_56745
Vesiclepedia VP_56745
Entrez Gene 56745
UniProt Q9QXP7  
 C1qtnf1 identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for C1qtnf1
Molecular Function
    protein binding GO:0005515 IPI
    collagen binding GO:0005518 IEA
    collagen binding GO:0005518 ISO
    identical protein binding GO:0042802 IPI
Biological Process
    positive regulation of cytosolic calcium ion concentration GO:0007204 IEA
    positive regulation of cytosolic calcium ion concentration GO:0007204 ISO
    negative regulation of platelet activation GO:0010544 ISO
    positive regulation of gene expression GO:0010628 IEA
    positive regulation of gene expression GO:0010628 ISO
    regulation of glucose metabolic process GO:0010906 IDA
    positive regulation of MAPK cascade GO:0043410 IDA
    positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051897 IDA
    negative regulation of platelet aggregation GO:0090331 IEA
    negative regulation of platelet aggregation GO:0090331 ISO
    positive regulation of aldosterone secretion GO:2000860 IEA
    positive regulation of aldosterone secretion GO:2000860 ISO
Subcellular Localization
    collagen trimer GO:0005581 IEA
    extracellular space GO:0005615 IBA
    extracellular space GO:0005615 IDA
    extracellular space GO:0005615 ISO
    plasma membrane GO:0005886 IEA
    plasma membrane GO:0005886 ISO
 Experiment description of studies that identified C1qtnf1 in sEVs
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for C1qtnf1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which C1qtnf1 is involved
No pathways found





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