Gene description for Xpo4
Gene name exportin 4
Gene symbol Xpo4
Other names/aliases B430309A01Rik
mKIAA1721
Species Mus musculus
 Database cross references - Xpo4
ExoCarta ExoCarta_57258
Entrez Gene 57258
UniProt Q9ESJ0  
 Xpo4 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Xpo4
Biological Process
    positive regulation of protein export from nucleus GO:0046827 ISO
    transport GO:0006810 IEA
    protein transport GO:0015031 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    nucleoplasm GO:0005654 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Xpo4 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Xpo4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Xpo4 is involved
No pathways found





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