Gene description for Gabarapl1
Gene name gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
Gene symbol Gabarapl1
Other names/aliases 3110025G09Rik
9130422N19Rik
AI196471
Apg8l
Atg8l
GECI
MNCb-0091
Species Mus musculus
 Database cross references - Gabarapl1
ExoCarta ExoCarta_57436
Entrez Gene 57436
UniProt Q8R3R8  
 Gabarapl1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Gabarapl1
Molecular Function
    microtubule binding GO:0008017 IBA
    protein binding GO:0005515 IPI
    GABA receptor binding GO:0050811 IBA
    cytoskeletal protein binding GO:0008092 ISA
    Tat protein binding GO:0030957 ISO
Biological Process
    membrane fusion GO:0061025 IBA
    autophagy GO:0006914 IEA
    mitochondrion degradation GO:0000422 IBA
    nucleophagy GO:0044804 IBA
    autophagosome assembly GO:0000045 IBA
Subcellular Localization
    dendrite membrane GO:0032590 ISO
    autophagosome GO:0005776 ISA
    cytosol GO:0005829 IBA
    endoplasmic reticulum GO:0005783 ISO
    Golgi apparatus GO:0005794 ISO
    autophagosome membrane GO:0000421 IBA
    membrane GO:0016020 IEA
    cytoplasm GO:0005737 IEA
    microtubule GO:0005874 IEA
    extrinsic component of membrane GO:0019898 IBA
    intracellular GO:0005622 ISO
    cytoskeleton GO:0005856 IEA
    cell body GO:0044297 ISO
    pre-autophagosomal structure GO:0000407 IBA
    dendrite cytoplasm GO:0032839 ISO
    mitochondrion GO:0005739 ISO
    cytoplasmic vesicle GO:0031410 IEA
 Experiment description of studies that identified Gabarapl1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Gabarapl1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gabarapl1 is involved
No pathways found





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