Gene description for Serinc4
Gene name serine incorporator 4
Gene symbol Serinc4
Other names/aliases -
Species Mus musculus
 Database cross references - Serinc4
ExoCarta ExoCarta_574418
Vesiclepedia VP_574418
Entrez Gene 574418
UniProt Q5XK03  
 Serinc4 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Serinc4
Biological Process
    phospholipid biosynthetic process GO:0008654 IEA
Subcellular Localization
    membrane GO:0016020 IBA
    membrane GO:0016020 IEA
 Experiment description of studies that identified Serinc4 in sEVs
1
Experiment ID 15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Serinc4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Serinc4 is involved
PathwayEvidenceSource
Metabolism IEA Reactome
Metabolism of amino acids and derivatives IEA Reactome
Serine biosynthesis IEA Reactome





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