Gene description for Zfp318
Gene name zinc finger protein 318
Gene symbol Zfp318
Other names/aliases 2610034E08Rik
D530032D06Rik
TZF
Znf318
Species Mus musculus
 Database cross references - Zfp318
ExoCarta ExoCarta_57908
Vesiclepedia VP_57908
Entrez Gene 57908
UniProt Q99PP2  
 Zfp318 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Zfp318
Molecular Function
    nucleic acid binding GO:0003676 IEA
    protein binding GO:0005515 IPI
    zinc ion binding GO:0008270 IEA
    protein homodimerization activity GO:0042803 IPI
    protein heterodimerization activity GO:0046982 IPI
Biological Process
    negative regulation of DNA-templated transcription GO:0045892 IBA
    negative regulation of DNA-templated transcription GO:0045892 IDA
    positive regulation of DNA-templated transcription GO:0045893 IBA
    positive regulation of DNA-templated transcription GO:0045893 IDA
    meiotic cell cycle GO:0051321 IEA
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IBA
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Zfp318 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Zfp318
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Umodl1  
Co-fractionation Mus musculus
2 Shank3  
Affinity Capture-MS Mus musculus
3 Amer1  
Co-fractionation Mus musculus
4 Phf6  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Zfp318 is involved
No pathways found





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