Gene description for Erbb2ip
Gene name Erbb2 interacting protein
Gene symbol Erbb2ip
Other names/aliases 1700028E05Rik
Erbin
mKIAA1225
Species Mus musculus
 Database cross references - Erbb2ip
ExoCarta ExoCarta_59079
Vesiclepedia VP_59079
Entrez Gene 59079
UniProt Q80TH2  
 Erbb2ip identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Erbb2ip
Molecular Function
    protein binding GO:0005515 IPI
    integrin binding GO:0005178 ISO
Biological Process
    protein targeting GO:0006605 IDA
Subcellular Localization
    nucleoplasm GO:0005654 ISO
    hemidesmosome GO:0030056 ISO
    cytoplasm GO:0005737 ISO
    nucleus GO:0005634 ISO
    cell junction GO:0030054 ISO
    basolateral plasma membrane GO:0016323 IDA
    plasma membrane GO:0005886 ISO
    membrane GO:0016020 IEA
    intracellular GO:0005622 IDA
 Experiment description of studies that identified Erbb2ip in exosomes
1
Experiment ID 907
MISEV standards
EM
EV Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
HSPA5
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
EV Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
HSPA5
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Erbb2ip
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Erbb2ip is involved
PathwayEvidenceSource
Signaling by ERBB2 IEA Reactome





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