Gene description for Cd14
Gene name CD14 molecule
Gene symbol Cd14
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Cd14
ExoCarta ExoCarta_60350
Entrez Gene 60350
UniProt Q63691  
 Cd14 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Cd14
Molecular Function
    protein binding GO:0005515 IPI
    lipopolysaccharide binding GO:0001530 ISO
    lipoteichoic acid binding GO:0070891 ISO
Biological Process
    positive regulation of tumor necrosis factor production GO:0032760 ISO
    response to magnesium ion GO:0032026 IEP
    cellular response to lipopolysaccharide GO:0071222 ISO
    response to ethanol GO:0045471 IEP
    response to molecule of bacterial origin GO:0002237 ISO
    positive regulation of cytokine secretion GO:0050715 IMP
    response to electrical stimulus GO:0051602 IEP
    cellular response to lipoteichoic acid GO:0071223 ISO
    positive regulation of endocytosis GO:0045807 ISO
    response to heat GO:0009408 IEP
    response to lipopolysaccharide GO:0032496 IEP
    innate immune response GO:0045087 IEA
    inflammatory response GO:0006954 IDA
    response to tumor necrosis factor GO:0034612 IMP
Subcellular Localization
    anchored component of membrane GO:0031225 IEA
    cell surface GO:0009986 IDA
    lipopolysaccharide receptor complex GO:0046696 TAS
    plasma membrane GO:0005886 IDA
    extracellular space GO:0005615 ISO
    extracellular exosome GO:0070062 ISO
    membrane raft GO:0045121 ISO
 Experiment description of studies that identified Cd14 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Cd14
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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