Gene description for Prmt1
Gene name	protein arginine methyltransferase 1
Gene symbol	Prmt1
Other names/aliases	Hrmt1l2
Species	Rattus norvegicus
Database cross references - Prmt1
ExoCarta	ExoCarta_60421
Vesiclepedia	VP_60421
Entrez Gene	60421
UniProt	Q63009
Prmt1 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Prmt1

Molecular Function     protein binding GO:0005515 IPI     N-methyltransferase activity GO:0008170 ISO     protein methyltransferase activity GO:0008276 IDA     protein methyltransferase activity GO:0008276 ISO     methyl-CpG binding GO:0008327 ISO     methyl-CpG binding GO:0008327 ISS     S-adenosylmethionine-dependent methyltransferase activity GO:0008757 TAS     protein-arginine N-methyltransferase activity GO:0016274 IDA     protein-arginine N-methyltransferase activity GO:0016274 IEA     protein-arginine N-methyltransferase activity GO:0016274 ISO     enzyme binding GO:0019899 ISO     snoRNP binding GO:0030519 IDA     protein-arginine omega-N monomethyltransferase activity GO:0035241 IBA     protein-arginine omega-N monomethyltransferase activity GO:0035241 IDA     protein-arginine omega-N monomethyltransferase activity GO:0035241 ISO     protein-arginine omega-N asymmetric methyltransferase activity GO:0035242 IBA     protein-arginine omega-N asymmetric methyltransferase activity GO:0035242 IDA     protein-arginine omega-N asymmetric methyltransferase activity GO:0035242 ISO     histone H3R17 methyltransferase activity GO:0035642 IEA     histone methyltransferase activity GO:0042054 IBA     histone methyltransferase activity GO:0042054 IDA     histone methyltransferase activity GO:0042054 ISO     identical protein binding GO:0042802 IPI     identical protein binding GO:0042802 ISO     histone H4R3 methyltransferase activity GO:0044020 ISO     histone H4R3 methyltransferase activity GO:0044020 ISS     mitogen-activated protein kinase p38 binding GO:0048273 ISO     histone H3K37 methyltransferase activity GO:0062122 IEA     histone H3R2 methyltransferase activity GO:0070611 IEA     GATOR1 complex binding GO:0106080 ISO     GATOR1 complex binding GO:0106080 ISS     histone H3R8 methyltransferase activity GO:0140592 IEA     histone H3K56 methyltransferase activity GO:0140759 IEA     histone H3R26 methyltransferase activity GO:0140903 IEA     histone H4K12 methyltransferase activity GO:0140984 IEA     S-adenosyl-L-methionine binding GO:1904047 IDA     S-adenosyl-L-methionine binding GO:1904047 ISO     S-adenosyl-L-methionine binding GO:1904047 ISS     histone H2AQ104 methyltransferase activity GO:1990259 IEA Biological Process     in utero embryonic development GO:0001701 ISO     chromatin remodeling GO:0006338 IBA     regulation of DNA-templated transcription GO:0006355 IBA     protein methylation GO:0006479 IDA     protein methylation GO:0006479 IDA     protein methylation GO:0006479 ISO     DNA damage response GO:0006974 ISO     positive regulation of cell population proliferation GO:0008284 ISO     positive regulation of cell population proliferation GO:0008284 ISS     RNA splicing GO:0008380 ISO     RNA splicing GO:0008380 ISS     peptidyl-arginine methylation GO:0018216 IDA     peptidyl-arginine methylation GO:0018216 ISO     peptidyl-arginine methylation, to asymmetrical-dimethyl arginine GO:0019919 IDA     peptidyl-arginine methylation, to asymmetrical-dimethyl arginine GO:0019919 IDA     regulation of BMP signaling pathway GO:0030510 ISO     neuron projection development GO:0031175 ISO     methylation GO:0032259 IEA     peptidyl-arginine omega-N-methylation GO:0035247 IDA     positive regulation of erythrocyte differentiation GO:0045648 IDA     positive regulation of erythrocyte differentiation GO:0045648 ISO     regulation of megakaryocyte differentiation GO:0045652 ISO     regulation of megakaryocyte differentiation GO:0045652 ISS     negative regulation of megakaryocyte differentiation GO:0045653 ISO     negative regulation of megakaryocyte differentiation GO:0045653 ISS     positive regulation of translation GO:0045727 ISO     negative regulation of JNK cascade GO:0046329 ISO     negative regulation of JNK cascade GO:0046329 ISS     S-adenosylmethionine metabolic process GO:0046500 IDA     positive regulation of hemoglobin biosynthetic process GO:0046985 IDA     cardiac muscle tissue development GO:0048738 ISO     cardiac muscle tissue development GO:0048738 ISS     protein homooligomerization GO:0051260 ISO     protein homooligomerization GO:0051260 ISS     cellular response to methionine GO:0061431 ISO     cellular response to methionine GO:0061431 ISS     liver regeneration GO:0097421 IEP     positive regulation of p38MAPK cascade GO:1900745 IDA     positive regulation of TORC1 signaling GO:1904263 ISO     positive regulation of TORC1 signaling GO:1904263 ISS     positive regulation of double-strand break repair via homologous recombination GO:1905168 ISO     positive regulation of double-strand break repair via homologous recombination GO:1905168 ISS Subcellular Localization     nucleus GO:0005634 IBA     nucleus GO:0005634 ISO     nucleoplasm GO:0005654 IEA     nucleoplasm GO:0005654 ISO     cytoplasm GO:0005737 ISO     lysosomal membrane GO:0005765 ISO     cytosol GO:0005829 IDA     cytosol GO:0005829 IEA     protein-containing complex GO:0032991 IDA     methylosome GO:0034709 ISO     methylosome GO:0034709 ISS