Gene description for RAB5C
Gene name RAB5C, member RAS oncogene family
Gene symbol RAB5C
Other names/aliases RAB5B
Species Bos taurus
 Database cross references - RAB5C
ExoCarta ExoCarta_613749
Entrez Gene 613749
UniProt Q58DS9  
 RAB5C identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for RAB5C
Molecular Function
    GTPase activity GO:0003924 IBA
    GTP binding GO:0005525 IEA
    GDP binding GO:0019003 ISS
Biological Process
    metabolic process GO:0008152 IBA
    endosome organization GO:0007032 IEA
    intracellular protein transport GO:0006886 IBA
    regulation of endocytosis GO:0030100 IBA
    Rab protein signal transduction GO:0032482 IBA
Subcellular Localization
    endocytic vesicle GO:0030139 IBA
    early endosome GO:0005769 IBA
    plasma membrane GO:0005886 IBA
    early endosome membrane GO:0031901 IEA
    melanosome GO:0042470 IEA
 Experiment description of studies that identified RAB5C in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RAB5C
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RAB5C is involved
PathwayEvidenceSource
Golgi Associated Vesicle Biogenesis IEA Reactome





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