Gene description for IRF6
Gene name interferon regulatory factor 6
Gene symbol IRF6
Other names/aliases -
Species Bos taurus
 Database cross references - IRF6
ExoCarta ExoCarta_614253
Entrez Gene 614253
UniProt Q08DD6  
 IRF6 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for IRF6
Molecular Function
    regulatory region DNA binding GO:0000975 IEA
    sequence-specific DNA binding transcription factor activity GO:0003700 ISS
    DNA binding GO:0003677 ISS
Biological Process
    positive regulation of transcription, DNA-templated GO:0045893 ISS
    negative regulation of cell proliferation GO:0008285 ISS
    transcription, DNA-templated GO:0006351 IEA
    mammary gland epithelial cell differentiation GO:0060644 ISS
Subcellular Localization
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 ISS
 Experiment description of studies that identified IRF6 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for IRF6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which IRF6 is involved
No pathways found





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