Gene description for SERPINA3-3
Gene name endopin 1b
Gene symbol SERPINA3-3
Other names/aliases SERPINA3-4
Species Bos taurus
 Database cross references - SERPINA3-3
ExoCarta ExoCarta_615103
Entrez Gene 615103
UniProt Q3ZEJ6  
 SERPINA3-3 identified in exosomes derived from the following tissue/cell type
Serum 19327352    
 Gene ontology annotations for SERPINA3-3
Molecular Function
    serine-type endopeptidase inhibitor activity GO:0004867 ISS
Biological Process
    negative regulation of endopeptidase activity GO:0010951 ISS
Subcellular Localization
    cytoplasmic vesicle GO:0031410 ISS
    extracellular space GO:0005615 ISS
    chromaffin granule GO:0042583 IEA
 Experiment description of studies that identified SERPINA3-3 in exosomes
1
Experiment ID 187
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors Ochieng J, Pratap S, Khatua AK, Sakwe AM.
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SERPINA3-3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SERPINA3-3 is involved
No pathways found





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