Gene description for MAPKAPK3
Gene name mitogen-activated protein kinase-activated protein kinase 3
Gene symbol MAPKAPK3
Other names/aliases MAPKAP-K3
MK-3
Species Bos taurus
 Database cross references - MAPKAPK3
ExoCarta ExoCarta_615215
Entrez Gene 615215
UniProt Q3SYZ2  
 MAPKAPK3 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for MAPKAPK3
Molecular Function
    ATP binding GO:0005524 IEA
    calmodulin-dependent protein kinase activity GO:0004683 IBA
    calcium-dependent protein serine/threonine kinase activity GO:0009931 IBA
    signal transducer activity GO:0004871 IBA
    mitogen-activated protein kinase binding GO:0051019 IBA
    protein serine/threonine kinase activity GO:0004674 ISS
    calmodulin binding GO:0005516 IBA
Biological Process
    macropinocytosis GO:0044351 ISS
    MAPK cascade GO:0000165 IBA
    cell surface receptor signaling pathway GO:0007166 IBA
    response to cytokine GO:0034097 ISS
    peptidyl-serine phosphorylation GO:0018105 IBA
    toll-like receptor signaling pathway GO:0002224 ISS
    response to lipopolysaccharide GO:0032496 ISS
    protein autophosphorylation GO:0046777 IBA
Subcellular Localization
    nuclear membrane GO:0031965 IEA
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified MAPKAPK3 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MAPKAPK3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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