Gene description for FLOT2
Gene name flotillin 2
Gene symbol FLOT2
Other names/aliases -
Species Bos taurus
 Database cross references - FLOT2
ExoCarta ExoCarta_615679
Entrez Gene 615679
UniProt A6QLR4  
 FLOT2 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for FLOT2
Biological Process
    negative regulation of gene expression GO:0010629 IEA
    establishment of protein localization to plasma membrane GO:0090002 IEA
    negative regulation of amyloid precursor protein catabolic process GO:1902992 IEA
    protein stabilization GO:0050821 IEA
    cell adhesion GO:0007155 IEA
Subcellular Localization
    flotillin complex GO:0016600 IEA
    acrosomal membrane GO:0002080 IEA
    endocytic vesicle GO:0030139 ISS
    extracellular exosome GO:0070062 IEA
    endosome GO:0005768 ISS
    perinuclear region of cytoplasm GO:0048471 IEA
    focal adhesion GO:0005925 IEA
 Experiment description of studies that identified FLOT2 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FLOT2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FLOT2 is involved
No pathways found





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