Gene description for ADI1
Gene name acireductone dioxygenase 1
Gene symbol ADI1
Other names/aliases Fe-ARD
MTCBP-1
Ni-ARD
Species Bos taurus
 Database cross references - ADI1
ExoCarta ExoCarta_615764
Entrez Gene 615764
UniProt Q3ZBL1  
 ADI1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ADI1
Molecular Function
    acireductone dioxygenase [iron(II)-requiring] activity GO:0010309 IEA
    iron ion binding GO:0005506 IEA
    oxidoreductase activity GO:0016491 ISS
Biological Process
    oxidation-reduction process GO:0055114 IEA
    L-methionine biosynthetic process from methylthioadenosine GO:0019509 ISS
Subcellular Localization
    nucleoplasm GO:0005654 IEA
    plasma membrane GO:0005886 ISS
    cytoplasm GO:0005737 ISS
    Golgi apparatus GO:0005794 IEA
    nucleus GO:0005634 ISS
 Experiment description of studies that identified ADI1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ADI1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ADI1 is involved
PathwayEvidenceSource
Methionine salvage pathway IEA Reactome





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