Gene description for CHMP2B
Gene name charged multivesicular body protein 2B
Gene symbol CHMP2B
Other names/aliases -
Species Bos taurus
 Database cross references - CHMP2B
ExoCarta ExoCarta_615954
Entrez Gene 615954
UniProt Q3SX42  
 CHMP2B identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for CHMP2B
Molecular Function
    protein domain specific binding GO:0019904 IEA
Biological Process
    regulation of centrosome duplication GO:0010824 IEA
    vacuolar transport GO:0007034 IEA
    cell separation after cytokinesis GO:0000920 IEA
    protein transport GO:0015031 IEA
    regulation of mitotic spindle assembly GO:1901673 IEA
    nucleus organization GO:0006997 IEA
    viral budding via host ESCRT complex GO:0039702 IEA
    mitotic metaphase plate congression GO:0007080 IEA
Subcellular Localization
    mitochondrion GO:0005739 IEA
    cytosol GO:0005829 IEA
    late endosome membrane GO:0031902 IEA
    extracellular exosome GO:0070062 IEA
    nucleoplasm GO:0005654 IEA
 Experiment description of studies that identified CHMP2B in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CHMP2B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CHMP2B is involved
PathwayEvidenceSource
Endosomal Sorting Complex Required For Transport (ESCRT) IEA Reactome





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