Gene description for NSDHL
Gene name NAD(P) dependent steroid dehydrogenase-like
Gene symbol NSDHL
Other names/aliases -
Species Bos taurus
 Database cross references - NSDHL
ExoCarta ExoCarta_616694
Entrez Gene 616694
UniProt Q3ZBE9  
 NSDHL identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for NSDHL
Molecular Function
    3-beta-hydroxy-delta5-steroid dehydrogenase activity GO:0003854 IEA
    sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity GO:0047012 IEA
Biological Process
    hair follicle development GO:0001942 IEA
    smoothened signaling pathway GO:0007224 IEA
    labyrinthine layer blood vessel development GO:0060716 IEA
    cholesterol biosynthetic process GO:0006695 IEA
    oxidation-reduction process GO:0055114 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    endoplasmic reticulum membrane GO:0005789 IEA
    lipid particle GO:0005811 IEA
 Experiment description of studies that identified NSDHL in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for NSDHL
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which NSDHL is involved
PathwayEvidenceSource
Cholesterol biosynthesis IEA Reactome





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