Gene description for COTL1
Gene name coactosin-like F-actin binding protein 1
Gene symbol COTL1
Other names/aliases -
Species Bos taurus
 Database cross references - COTL1
ExoCarta ExoCarta_617165
Entrez Gene 617165
UniProt Q2HJ57  
 COTL1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for COTL1
Molecular Function
    actin binding GO:0003779 IEA
    enzyme binding GO:0019899 IEA
Biological Process
    defense response to fungus GO:0050832 IEA
    leukotriene biosynthetic process GO:0019370 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    cytoskeleton GO:0005856 IEA
    nuclear membrane GO:0031965 IEA
    extracellular exosome GO:0070062 IEA
 Experiment description of studies that identified COTL1 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for COTL1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which COTL1 is involved
No pathways found





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