Gene description for COMT
Gene name catechol-O-methyltransferase
Gene symbol COMT
Other names/aliases -
Species Bos taurus
 Database cross references - COMT
ExoCarta ExoCarta_618278
Entrez Gene 618278
UniProt A7MBI7  
 COMT identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for COMT
Molecular Function
    magnesium ion binding GO:0000287 IEA
    catechol O-methyltransferase activity GO:0016206 IEA
Biological Process
    cellular response to phosphate starvation GO:0016036 IEA
    methylation GO:0032259 IEA
    dopamine catabolic process GO:0042420 IEA
    neurotransmitter catabolic process GO:0042135 IEA
Subcellular Localization
    mitochondrion GO:0005739 IEA
    extracellular exosome GO:0070062 IEA
    plasma membrane GO:0005886 IEA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified COMT in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for COMT
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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