Gene description for COMT
Gene name catechol-O-methyltransferase
Gene symbol COMT
Other names/aliases -
Species Bos taurus
 Database cross references - COMT
ExoCarta ExoCarta_618278
Entrez Gene 618278
UniProt A7MBI7  
 COMT identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for COMT
Molecular Function
    magnesium ion binding GO:0000287 IEA
    catechol O-methyltransferase activity GO:0016206 IEA
Biological Process
    cellular response to phosphate starvation GO:0016036 IEA
    methylation GO:0032259 IEA
    dopamine catabolic process GO:0042420 IEA
    neurotransmitter catabolic process GO:0042135 IEA
Subcellular Localization
    mitochondrion GO:0005739 IEA
    extracellular exosome GO:0070062 IEA
    plasma membrane GO:0005886 IEA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified COMT in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for COMT
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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