Gene description for Surf4
Gene name surfeit 4
Gene symbol Surf4
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Surf4
ExoCarta ExoCarta_619346
Vesiclepedia VP_619346
Entrez Gene 619346
 Surf4 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Surf4
Molecular Function
    cargo receptor activity GO:0038024 ISO
    COPII receptor activity GO:0097020 ISO
Biological Process
    endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888 ISO
    Golgi organization GO:0007030 ISO
    positive regulation of organelle organization GO:0010638 ISO
    regulation of lipid transport GO:0032368 ISO
    protein exit from endoplasmic reticulum GO:0032527 ISO
    early endosome to Golgi transport GO:0034498 ISO
    lipoprotein transport GO:0042953 ISO
    lipid homeostasis GO:0055088 ISO
    COPII-coated vesicle cargo loading GO:0090110 ISO
    lipid export from cell GO:0140353 ISO
Subcellular Localization
    Golgi membrane GO:0000139 IEA
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum membrane GO:0005789 IEA
    endoplasmic reticulum-Golgi intermediate compartment GO:0005793 ISO
    Golgi apparatus GO:0005794 ISO
    cytosol GO:0005829 ISO
    COPII-coated ER to Golgi transport vesicle GO:0030134 ISO
    nuclear membrane GO:0031965 ISO
    endoplasmic reticulum-Golgi intermediate compartment membrane GO:0033116 IEA
    endoplasmic reticulum exit site GO:0070971 ISO
 Experiment description of studies that identified Surf4 in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Surf4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Surf4 is involved
No pathways found





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