Gene description for Acads
Gene name acyl-CoA dehydrogenase, C-2 to C-3 short chain
Gene symbol Acads
Other names/aliases Scad
Species Rattus norvegicus
 Database cross references - Acads
ExoCarta ExoCarta_64304
Vesiclepedia VP_64304
Entrez Gene 64304
UniProt P15651  
 Acads identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Acads
Molecular Function
    acyl-CoA dehydrogenase activity GO:0003995 IDA
    acyl-CoA dehydrogenase activity GO:0003995 IEA
    acyl-CoA dehydrogenase activity GO:0003995 ISO
    acyl-CoA dehydrogenase activity GO:0003995 NAS
    short-chain fatty acyl-CoA dehydrogenase activity GO:0016937 IBA
    protein homodimerization activity GO:0042803 IDA
    protein homodimerization activity GO:0042803 IPI
    flavin adenine dinucleotide binding GO:0050660 IDA
    flavin adenine dinucleotide binding GO:0050660 IEA
    FAD binding GO:0071949 IDA
Biological Process
    fatty acid beta-oxidation using acyl-CoA dehydrogenase GO:0033539 IBA
    fatty acid beta-oxidation using acyl-CoA dehydrogenase GO:0033539 IDA
    fatty acid beta-oxidation using acyl-CoA dehydrogenase GO:0033539 IEA
    fatty acid beta-oxidation using acyl-CoA dehydrogenase GO:0033539 ISO
    response to starvation GO:0042594 IEP
    butyrate catabolic process GO:0046359 IBA
    butyrate catabolic process GO:0046359 IDA
    carboxylic acid catabolic process GO:0046395 IEA
    response to glucocorticoid GO:0051384 IEP
Subcellular Localization
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IEA
    mitochondrion GO:0005739 ISO
    mitochondrial matrix GO:0005759 IDA
    centrosome GO:0005813 IEA
    centrosome GO:0005813 ISO
    mitochondrial membrane GO:0031966 IDA
 Experiment description of studies that identified Acads in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Acads
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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