Gene description for Acads
Gene name acyl-CoA dehydrogenase, C-2 to C-3 short chain
Gene symbol Acads
Other names/aliases Scad
Species Rattus norvegicus
 Database cross references - Acads
ExoCarta ExoCarta_64304
Entrez Gene 64304
UniProt P15651  
 Acads identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Acads
Molecular Function
    fatty-acyl-CoA binding GO:0000062 IDA
    flavin adenine dinucleotide binding GO:0050660 IDA
    butyryl-CoA dehydrogenase activity GO:0004085 TAS
    acyl-CoA dehydrogenase activity GO:0003995 NAS
Biological Process
    response to glucocorticoid GO:0051384 IEP
    protein homotetramerization GO:0051289 IDA
    butyrate catabolic process GO:0046359 IDA
    fatty acid beta-oxidation GO:0006635 TAS
    response to starvation GO:0042594 IEP
    fatty acid beta-oxidation using acyl-CoA dehydrogenase GO:0033539 IDA
Subcellular Localization
    mitochondrion GO:0005739 ISO
    nucleus GO:0005634 ISO
    mitochondrial matrix GO:0005759 TAS
    mitochondrial membrane GO:0031966 IDA
 Experiment description of studies that identified Acads in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Acads
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Acads is involved
PathwayEvidenceSource
Beta oxidation of butanoyl-CoA to acetyl-CoA IEA Reactome
Beta oxidation of hexanoyl-CoA to butanoyl-CoA IEA Reactome





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